GelControl™ Inserts

GelControl™ inserts turn fragile hydrogel domes into stable, repeatable 3D constructs, improving handling, imaging accessibility, and well-to-well consistency without impacting cellular viability.

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Want to test GelControl™ in your workflow first? Request an Evaluation Kit.

How GelControl Inserts Enhance Reproducibility In 3D Cell Culture Workflows

Shape & Positioning

GEL ONLY
WITH GELCONTROL™
Unsupported gel-only cultures can vary in shape and position within the well. GelControl™ creates more consistent, centered hydrogel constructs for improved workflow reproducibility.

Shape & Positioning

GEL-ONLY
WITH GEL-CONTROL
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Shape & Positioning

Shape and position of a thick hydrogel within a well can dramatically influence nutrient diffusion and necrotic core formation through culture duration.

GelControl™ inserts provide a mold to simplify pipetting workflow and create highly repeatable hydrogel shapes consistently positioned in the center of wells.

Handling & Transfer

GEL ONLY
WITH GELCONTROL™
Gel-only cultures are prone to deformation and sample loss during handling and transfer. GelControl™ provides stable support for more reliable manipulation throughout the workflow.

Handling & Transfer

GEL-ONLY
WITH GEL-CONTROL
VIEW EMPIRICAL IMAGES

Handling & Transfer

Conventional 3D hydrogel constructs routinely undergo pipetting-induced deformations during media change, cell-mediated contractions, floating, and mechanical insults with spatula or pipette during transfer.

GelControl™ inserts mechanically support soft constructs with a fine microfiber grid and a large handle to simplify and streamline handling and transfer while removing invasive mechanical interventions.

Imaging Accessibility

GEL ONLY
WITH GELCONTROL™
Gel-only cultures can be difficult to image because variable thickness and movement reduce optical accessibility. GelControl™ creates thinner, more consistent constructs for improved imaging access.

Imaging Accessibility

GEL-ONLY
WITH GEL-CONTROL
VIEW EMPIRICAL IMAGES

Imaging Accessibility

Thick hydrogel constructs are challenging to image because of variable thickness and unbounded mounting that leads to movement during imaging.

GelControl™ inserts are designed to image from below. A fine and highly porous microgrid keeps soft hydrogels anchored to the bottom with consistent thickness that facilitates imaging accessibility.

Our Unique Approach

Designed to Improve Reproducibility in Soft-Gel 3D Culture Workflows

A microarchitectured insert that adds mechanical support to soft-gels. Wings and center ring keep hydrogel dome shapes consistent and centered, while the handle allows for easier handling and transfer without disrupting cells or causing sample loss.
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Want to test GelControl™ in your workflow? Request an Evaluation Kit.

Benefits to 3D Culture Workflows With Soft Hydrogels

Improved Reproducibility

Simplified workflow with more consistent geometries.

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Imaging Accessibility

Samples are easy to locate and have consistent thickness leading to crisp image quality and reliable data.

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Handling & Transfer

Move and manipulate delicate constructs with ease and minimal damage.

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Reduced Sample Loss

Designed to simplify workflow by supporting soft gels.

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Cellular Health / Viability

Inserts do not influence cellular viability.

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Centralizes Gel Shape & Position

GelControl™ inserts reinforce softer, lower-concentration hydrogels.

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Applications

Organoid Development

Maintain construct geometry during long-term culture.

Therapeutic Efficacy & Toxicity Testing

Reduce variability in 3D models for more reproducible screening results.

Imaging Workflows

Keep samples stable and in focus for consistent imaging and analysis.

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